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phenobarbital will decrease the level or result of meloxicam by impacting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Not known.phenobarbital will reduce the level or outcome of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Gals shouldn't select estradiol valerate/dienogest as t